Botulinum toxin a may be efficacious as treatment for jaw tremor in Parkinson's disease
Identifieur interne : 003560 ( Main/Exploration ); précédent : 003559; suivant : 003561Botulinum toxin a may be efficacious as treatment for jaw tremor in Parkinson's disease
Auteurs : Susanne A. Schneider [Royaume-Uni] ; Mark J. Edwards [Royaume-Uni] ; Carla Cordivari [Royaume-Uni] ; William N. Macleod [Royaume-Uni] ; Kailash P. Bhatia [Royaume-Uni]Source :
- Movement Disorders [ 0885-3185 ] ; 2006-10.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Bontoxilysin, Botulinum Toxins, Type A (administration & dosage), Electromyography (drug effects), Female, Humans, Injections, Intramuscular, Jaw, Jaw Diseases (drug therapy), Male, Masseter muscle, Middle Aged, Nervous system diseases, Parkinson Disease (drug therapy), Parkinson disease, Parkinson's disease, Pilot Projects, Treatment, Treatment Outcome, Tremor, Tremor (drug therapy), botulinum toxin A, jaw tremor, masseter muscle, tremor.
- MESH :
- chemical , administration & dosage : Botulinum Toxins, Type A.
- drug effects : Electromyography.
- drug therapy : Jaw Diseases, Parkinson Disease, Tremor.
- Aged, Aged, 80 and over, Female, Humans, Injections, Intramuscular, Male, Middle Aged, Pilot Projects, Treatment Outcome.
Abstract
Jaw tremor in Parkinson's disease (PD) may not respond well to conventional treatment. It causes embarrassment and social handicap. We piloted the use of botulinum toxin (BTX) injections in three patients with PD jaw tremor. BTX A (Dysport; mean, 53 U; range, 30–100 U) was given into each masseter muscle. Outcome was assessed by subjective and clinical improvement and by video recording before and 4 to 9 weeks after injections. There was an excellent response in all without side effects. BTX injections into the masseter may effectively improve jaw tremor and be useful in PD and other conditions. © 2006 Movement Disorder Society
Url:
DOI: 10.1002/mds.21019
Affiliations:
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Le document en format XML
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<term>Electromyography (drug effects)</term>
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<front><div type="abstract" xml:lang="en">Jaw tremor in Parkinson's disease (PD) may not respond well to conventional treatment. It causes embarrassment and social handicap. We piloted the use of botulinum toxin (BTX) injections in three patients with PD jaw tremor. BTX A (Dysport; mean, 53 U; range, 30–100 U) was given into each masseter muscle. Outcome was assessed by subjective and clinical improvement and by video recording before and 4 to 9 weeks after injections. There was an excellent response in all without side effects. BTX injections into the masseter may effectively improve jaw tremor and be useful in PD and other conditions. © 2006 Movement Disorder Society</div>
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